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Request for Applications 2024-003: MATRIX Technology Accelerator Domain 1

Seed Grants for HIV Prevention Products

This is an opportunity to apply for funding to advance research applications for the development of new primary HIV prevention approaches.  For the purposes of this RFA, primary HIV prevention is defined as the inhibition of HIV transmission from an infected individual to an uninfected woman using a drug or device that prevents systemic or vaginal virus infection. Applicants from a wide range of United States, European Union, United Kingdom, Kenyan, South African, and Zimbabwean institutions are invited to apply to this request for applications sponsored by the Microbicide R&D to Advance HIV Prevention Technologies through Responsive Innovation and eXcellence (MATRIX) consortium and United States Agency for International Development.

We are seeking innovative research applications for the development of new HIV prevention drug and strategies, multipurpose prevention technologies (MPTs), and technologies that enable HIV prevention strategy development and have the potential to strengthen capacity in targeted countries. Established researchers, research consortia, students, postdoctoral fellows, and new investigators establishing laboratories and/or seeking tenure from the United States, European Union, United Kingdom, Kenya, South Africa, and Zimbabwe are encouraged to apply. Proposed research must be driven by milestones, go/no-go criteria, and timelines, and must target development of HIV prevention for one or more of the following populations: adolescent girls and young women, pregnant and breastfeeding people, and female sex workers. Applications are limited to projects with costs of US$150,000 and a duration of 18 months. PATH, a member of the MATRIX consortium, will oversee the application submission and award processes using an oversight structure that draws from US- and Africa-based administrators.

Instructions on how to apply and templates for the application are below:

Key dates

Release of request for applicationsFebruary 1, 2024
Letter of intent dueFebruary 22, 2024 (8:00AM Pacific time)
Fact-finding questions dueFebruary 22, 2024 (8:00AM Pacific time)
Responses to fact-finding questions provided to applicantsMarch 1, 2024 (8:00AM Pacific time)
Applications dueApril 1, 2024 (8:00AM Pacific time)
Estimated decision notificationMay 15, 2024
Estimated project start dateJuly 1, 2024

Note that MATRIX reserves the right to modify this schedule as needed. Parties who express interest will be notified by email of any changes.

This request for applications expires on April 2, 2024.

DescriptionDateSize
RFA2024-003 Documents
Instructions (Download) 2024-01-31407.01 KB
Template for Main Application (Download) 2024-01-31133.1 KB
Template for Budget Narrative (Download) 2024-01-31130.47 KB
Template for Detailed Budget (Download) 2024-01-3152.62 KB
Financial Risk Assessment Questionnaire (Download) 2024-01-31241.23 KB
Responses to fact-finding questions (Download) 2024-02-23103.51 KB