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Griffithsin Fast Dissolving Vaginal Insert

The Griffithsin (GRFT) fast-dissolving insert (FDI) is developed by Population Council. This fast-dissolving vaginal insert is an on-demand HIV prevention product for women and girls, including pregnant and breastfeeding women, designed for over-the-counter distribution as a non-antiretroviral option. Manufacturable in low- and middle-income countries, the safe, discreet, user-controlled, and portable fast-dissolving insert has activity against HIV, HSV-2, and HPV, and may be suitable for over-the-counter distribution.  Building on favorable outcomes in animal models, the GRFT FDI will be advanced through pre-clinical studies, production of good manufacturing practice FDIs, and the conduct of Phase 1 trials.

Image of Mice FDIs Product from PopCouncil
Mice FDIs
Image of Macaque FDIs (non-human primate) product by PopCouncil
Macaque (Non-human primate) FDIs